SYSTEMATIC REVIEW REGISTER

This review will consider any studies that include sports men and women of any age group, participating in both recreational and elite sports. Participants with or without ankle injuries will be included. Studies reporting on athletes with other musculoskeletal injuries other than ankle injuries or post-surgical cases will be excluded from this review. 

Registered health care providers regardless of age, gender or years of experience.

Patients with mild-moderate symptoms that are at high risk of progression to severe disease.

POPULATION:
Patients diagnosed with Orofacial pain AND
Inclusion criteria:
i. Age > 18 years
ii. A diagnosis of Orofacial pain.

Exclusion criteria:
Conditions that can influence pain sensitivity, such as systemic inflammatory connective tissue diseases (e.g., rheumatoid arthritis); whiplash-associated disorders; chronic widespread muscle pain conditions (e.g., fibromyalgia); neuropathic pain or neurological disorders (e.g., oromandibular dystonia); pain of dental origin; pregnancy or lactation; high blood pressure; and ongoing dental treatment. Another exclusion criterion is medication that could interfere with the blood analysis or pain sensitivity (e.g., anticoagulant treatment and analgesic consumption within 1 week before the experiment, for example, of paracetamol, NSAIDs (Non-steroidal anti-inflammatory drugs), salicylate drugs, or opioids) or that could influence pain perception (e.g., anti-depressants or antiepileptic drugs). Exclusion criteria will be assessed in each subject by taking a medical history.
 

Adults and children

Inclusion criteria:
Adult subjects (18years) diagnosed with Obstructive Sleep Apnea

Exclusion Criteria:
Pediatric Obstructive Sleep Apnea, studies on patients suffering from conditions other than OSA.
 

The population/problem for the proposed review would be the variations in protocols used to prepare various forms of platelet concentrates. 
 
Platelet concentrates are known as blood derivatives rich in growth factors, cytokines and matrix proteins. The release of these bioactive mediators positively affect the wound healing process and bone regeneration. There are various forms of platelet concentrates based on the protocols used in preparation by varying the centrifugation speed(rcf/rpm), number of cycles, time, test tubes and additives used etc. 
( The platelet concentrates included in this study are fibrin glue, fibrin sealant, platelet rich plasma(PRP), concentrated growth factor(CGF), plasma rich in growth fcators(PRGF), platelet rich fibrin(PRF), platelet rich fibrin matrix(PRFM), leuokocyte and platelet rich fibrin(L-PRF), advanced platelet rich fibrin(A-PRF), injectable platelet rich fibrin(i-PRF), titanium platelet rich fibrin(T-PRF).

The review will consider studies that include adults 18 years or over, diagnosed with CHD, adults with co-morbidities in any setting will also be included.

Patients between 15- to 40-years-old diagnosed with conventional OSCC regardless of country, race and gender who had undergone treatment of the primary lesion.

Critically ill children (birth to 18 years) admitted to a pediatric intensive care unit (PICU) and their family members. Family members will include anyone who self-identifies as a family member. We will includes studies that examine the impact for family presence on healthcare providers, and define healthcare providers as members of the child's PICU care team who interact directly with parents and children at the bedside.