What is the effectiveness of leukocyte reduction comparing post-storage filter (bedside) and pre-storage filters ("bench" or in-line) regarding the occurrence of TRs and bacterial infection, in addition to the length of stay and death of patients undergoing reduced blood transfusion?
This review will consider studies that include patients of any age, sex and race who received reduced blood transfusion.
Use of a post-storage filter (bedside) to remove leukocytes of any brand and type.
The following outcomes will be considered: length of hospital stay, TRs, bacterial infection and hospital death.
For length of stay, the number of days the patient stayed in the hospital will be considered. For TRs, the type of reaction (immediate - within 24 hours after the transfusion and late - after 24 hours after the transfusion) and the diagnosis of the confirmed reaction (ALO-HLA, FNHTR or TRALI) will be observed. For infection, the occurrence of bacterial infection will be confirmed on laboratory examination. And for hospital death, this event confirmed, from any cause, after the transfusion will be considered.